Pathology of idiopathic megarectum and megacolon

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Pathology of idiopathic megarectum and megacolon.

BACKGROUND The aetiology and pathology of both idiopathic megarectum and idiopathic megacolon are unknown. In particular, it is unknown whether there are abnormalities involving enteric nerves or smooth muscle. METHODS Resected tissue was examined from 24 patients who underwent surgery for idiopathic megarectum, from six patients who had tissue resected for idiopathic megacolon, and 17 contro...

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Idiopathic megarectum and megacolon.

A 56-year-old female with a prior medical history of congenital mental retardation, hypercholesterolemia, and hypothyroidism consulted for severe constipation refractory to laxatives, which required enemas for evacuation, associated with abdominal distension and weight loss –8 kg over the last six months–. Physical examination revealed a hard, long, rounded mass measuring 8 x 10 cm in the centr...

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Colectomy for idiopathic megarectum and megacolon.

The outcome in 40 patients who underwent colectomy for idiopathic megacolon and megarectum over an 18 year period was evaluated. All patients had a radiologically dilated bowel and a bowel frequency of less than two per week. Twenty two patients had a caecorectal anastomosis, 11 had an ileorectal anastomosis (including one with a previous caecorectal anastomosis and four with a previous sigmoid...

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Clinical features of idiopathic megarectum and idiopathic megacolon.

BACKGROUND Dilatation of the rectum and/or colon, in the absence of demonstrable organic disease, is an uncommon and poorly characterised condition. AIMS To characterise the clinical and diagnostic features, and response to treatment, of patients with idiopathic megarectum (IMR) and idiopathic megacolon (IMC). METHODS A retrospective review was undertaken of all patients operated on for the...

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Hirschsprung's disease and idiopathic megacolon in adults and adolescents.

The distinction between Hirschsprung's disease and idiopathic megacolon in childhood dates from the classic clinical, radiological, and histological studies of Bodian, Stephens, and Ward. This article describes clinical experience over 15 years of 94 patients in whom megacolon of these two types was recognised for the first time after the age of 10, to illustrate the problems of diagnosis and t...

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ژورنال

عنوان ژورنال: Gut

سال: 1997

ISSN: 0017-5749,1468-3288

DOI: 10.1136/gut.41.2.252